The DUROLANE Difference

Shown to significantly improve patient quality of life as early as 2 weeks after an injection, DUROLANE effectiveness has been proven in more clinical studies than any other single-injection hyaluronic acid knee therapy:20

DUROLANE has the highest reported molecular weight of any HA–1015 kDa.*43,46

*Based on theoretical calculations


Uniquely formulated for superior single-injection performance

Created using an innovative stabilizing technology, DUROLANE was purposefully designed to be a powerful, single-injection hyaluronic acid therapy.10

DUROLANE is a high-molecular-weight, nonavian hyaluronic acid, stabilized with a carefully controlled cross-linking process to increase residence time in the knee joint.10,15,33

Choose DUROLANE for longer-lasting results

  • Total joint residence time of approximately 150 days based on a half-life of 30 days35,48
  • A half-life of 30 days (approximately 4 weeks) in the knee joint in a single-injection treatment regimen35
  • The longest reported half-life of any HA32-35

‡The clinical relevance of this information has not been determined.